Research Article
A Facile Solvent Free Microwave Induced Synthesis and Antibacterial Activity of Some 3-(2’-Hydroxyphenyl)-5-(Substituted Aryl)-2- Pyrazoline-N1-Caboxaldehydes
BIRBAL BAJIA and Y. K. SRIVASTAVA
ABSTRACT
A novel one pot formylation of 3-(2’-hydroxyphenyl)-5-(substituted aryl) 2-pyrazolines has been carried out using microwave irradiation with formic acid. The solvent free reaction afforded title compounds in 80-90% yield with high purity. All synthesized compounds were tested for their antibacterial activity using standard drug.
Received 9 November 2006; Revised 24 November 2006; Accepted 24 December 2006